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ARHGDIA antibody (Internal Region)
ARHGDIA
Reactivity: Human, Mouse, Rat, Dog, Cow
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-ARHGDIA Antibody
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Target
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ARHGDIA
(rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))
Binding Specificity
All epitopes for ARHGDIA antibodies
Internal Region
Reactivity
Human, Mouse, Rat, Dog, Cow
Host
All hosts for ARHGDIA antibodies
Goat
Clonality
All clonalities for ARHGDIA antibodies
Polyclonal
Conjugate
All conjugates for ARHGDIA antibodies
This ARHGDIA antibody is un-conjugated
Application
All applications for ARHGDIA antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
C-QLAQIAAENE
Specificity
Recognizes ARHGDIA.
Cross-Reactivity (Details)
Species reactivity (expected):Human, Dog, Cow. Species reactivity (tested):Mouse, Rat.
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Immunogen
Peptide with sequencefrom the internal region of the protein sequence according to NP_004300.1. Genename: ARHGDIA
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Discover our top product ARHGDIA Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for ARHGDIA
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Target
ARHGDIA
(rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))
Alternative Name
ARHGDIA / GDIA1 (ARHGDIA Products )
Synonyms
GDIA1 antibody, NPHS8 antibody, RHOGDI antibody, RHOGDI-1 antibody, Bles01 antibody, zgc:55554 antibody, zgc:77681 antibody, wu:fa96g11 antibody, ARHGDIA antibody, NV15502 antibody, 5330430M07Rik antibody, Gdi-1 antibody, Rho-GDI antibody, RhoDGI antibody, RhoGDI-1 antibody, arhgdia antibody, MGC84535 antibody, gdia1 antibody, rhogdi antibody, rhogdi-1 antibody, rhogdi1 antibody, Rho GDP dissociation inhibitor alpha antibody, Rho GDP dissociation inhibitor (GDI) alpha antibody, rho GDP-dissociation inhibitor 2 antibody, Rho GDP dissociation inhibitor (GDI) alpha L homeolog antibody, ARHGDIA antibody, Arhgdia antibody, arhgdia antibody, LOC100120432 antibody, arhgdia.L antibody
Background
Rho GDP-dissociation inhibitor 1, also known ARHGDIA, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. Localized to the cytoplasm, ARHGDIA inhibits the dissociation of GDP from Rho proteins, thereby preventing GTP from binding to and subsequently activating Rho proteins. In humans ARHGDIA can be phosphorylated at Ser 101 by p21-activated kinase, an event that inhibits ARHGDIA activity and may result in positive feedback regulation of certain ARHGDIA target proteins.Synonyms: Rho GDI 1, Rho GDP-dissociation inhibitor 1, Rho-GDI alpha, RhoGDI1
Gene ID
396
NCBI Accession
NP_004300
UniProt
P52565
Pathways
Neurotrophin Signaling Pathway
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