ALDH5A1 antibody (Internal Region)

Catalog No. ABIN569590

This Goat Polyclonal antibody specifically detects ALDH5A1 in WB and EIA. It exhibits reactivity toward Human, Rat, Mouse, Cow and Dog.

Quick Overview for ALDH5A1 antibody (Internal Region) (ABIN569590)

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Reactivity: Human, Rat, Mouse, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This ALDH5A1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ALDH5A1 Antibody

Binding Specificity: AA 301-312, Internal Region

Sequence: C-TGKILLHHAA NS

Specificity: This antibody is expected to recognize both reported isoforms (NP_733936.1, NP_001071.1).

Cross-Reactivity (Details): Species reactivity (expected):Canine (Dog), Bovine.
Species reactivity (tested):Human, Mouse, Rat.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_733936.1 NP_001071.1.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ALDH5A1

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Alternative Name: ALDH5A1 / SSADH

Background: Defects in ALDH5A1 are the cause of succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) [MIM:271980]. SSADH deficiency is a rare inborn error in the metabolism of 4-aminobutyric acid (GABA) which leads to accumulation of 4-hydroxybutyric acid in physiologic fluids of patients. The disease is characterized by severe ataxia and by mildly retarded psychomotor development.Synonyms: Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, Succinate-semialdehyde dehydrogenase, mitochondrial

Molecular Weight: 58.7kDa (NP_733936.1).

Gene ID: 7915

NCBI Accession: NP_001071

UniProt: P51649

Pathways: Monocarboxylic Acid Catabolic Process