BCL2A1 antibody (Internal Region)

Catalog No. ABIN569592

Product Details anti-BCL2A1 Antibody

Target: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Binding Specificity: Internal Region

Reactivity: Human, Pig, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This BCL2A1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-NVVSVDTART

Specificity: This antibody is expected to recognize both reported isoforms (NP_004040.1 and NP_001108207.1).

Cross-Reactivity (Details): Species reactivity (expected):Dog, Cow, Pig.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_004040.1, NP_001108207.1.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for BCL2A1

Target: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Abstract: BCL2A1 Products

Synonyms: ACC-1 antibody, ACC-2 antibody, BCL2L5 antibody, BFL1 antibody, GRS antibody, HBPA1 antibody, Bcl2a1d antibody, BCL2A1 antibody, BCL2 related protein A1 antibody, BCL2-related protein A1 antibody, BCL2A1 antibody, Bcl2a1 antibody

Background: A1 (also designated Bfl-1) is a Bcl-2 family protein that dimerizes with both Bcl-2 and Bax, and has been identified as a hematopoietic-specific, early inducible gene. Although A1 demonstrated properties similar to those of Bcl-2, its function may be more temporally regulated during myeloid differentiation and is dependent on additional growth stimuli to confer its life promoting properties. A1 is abundantly expressed in bone marrow and at low levels in other tissues. A1 expression has been correlated to stomach cancer.Synonyms: BCL2A1, BCL2L5, BFL1, Bcl-2-like protein 5, Bcl-2-related protein A1, GRS, HBPA1, Hemopoietic-specific early response protein, Protein BFL-1

Molecular Weight: 20.1kDa (NP_004040.1).

Gene ID: 597

NCBI Accession: NP_004040

UniProt: Q16548