SLC44A1 antibody (C-Term) (PE)

Catalog No. ABIN576910

Product Details anti-SLC44A1 Antibody (PE)

Target: SLC44A1 (Solute Carrier Family 44, Member 1 (SLC44A1))

Binding Specificity: C-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC44A1 antibody is conjugated to PE

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Specific for the C-terminal variant of human CDw92 (isoform 3), also known as CTL1, a 70kD multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells. CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine. Clone VIM-15b is reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells (Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10.

Purification: Affinity purified

Immunogen: MV4-11 acute monocyte leukaemia cells.

Type of Immunogen: Cells

Clone: VIM-15b

Isotype: IgG2b

Application Details

Application Notes: Approved: Flo (1:1 - 1:10), IHC, IHC-Fr, IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 4°C, avoid freezing.

Target Details for SLC44A1

Target: SLC44A1 (Solute Carrier Family 44, Member 1 (SLC44A1))

Alternative Name: SLC44A1 / CD92 (SLC44A1 Products)

Synonyms: CD92 antibody, CDW92 antibody, CHTL1 antibody, CTL1 antibody, RP11-287A8.1 antibody, Cdw92 antibody, Ctl1 antibody, 2210409B22Rik antibody, 4833416H08Rik antibody, AW547365 antibody, SLC44A1 antibody, slc44a1 antibody, zgc:112201 antibody, ctl1 antibody, solute carrier family 44 member 1 antibody, solute carrier family 44, member 1 antibody, solute carrier family 44 (choline transporter), member 1a antibody, solute carrier family 44 (choline transporter), member 1 antibody, choline transporter-like protein 1 antibody, Choline transporter-like protein 1 antibody, solute carrier family 44 (choline transporter), member 1 L homeolog antibody, SLC44A1 antibody, Slc44a1 antibody, slc44a1a antibody, slc44a1 antibody, LOC100404101 antibody, chtl-1 antibody, slc44a1.L antibody

Background: Name/Gene ID: SLC44A1
Subfamily: Choline transporter-like
Family: Transporter

Synonyms: SLC44A1, CD92 antigen, CTL1, RP11-287A8.1, CD92, CDW92, CDW92 antigen, CHTL1

Gene ID: 23446