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CD45RO antibody (CD45RO) (Biotin)

Details for Product anti-CD45RO Antibody No. ABIN610095, Supplier: Log in to see
Antigen
Reactivity
Human
203
45
9
9
3
2
Host
Mouse
206
Clonality (Clone)
Monoclonal ()
Conjugate
This CD45RO antibody is conjugated to Biotin
21
19
7
6
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
179
79
77
63
56
52
50
49
26
3
1
1
1
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Immunogen Cultured human T cell line-CA-1.
Clone UCHL1
Isotype IgG2a
Specificity CD45RO isoform of about 180 kd.
Purification Protein A Column
Alternative Name CD45RO
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flo, IHC-P
Restrictions For Research Use only
Format Liquid
Buffer 50 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5% Glycerol, 0.2% BSA, 0.04% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at +4°C. DO NOT FREEZE.
Product cited in: Furuta, Miura, Copeland, Shang, Oshima, Kamata: "Light Chain 3 associates with a Sos1 guanine nucleotide exchange factor: its significance in the Sos1-mediated Rac1 signaling leading to membrane ruffling." in: Oncogene, Vol. 21, Issue 46, pp. 7060-6, 2002 (PubMed).

Kardinal, Konkol, Lin, Eulitz, Schmidt, Estrov, Talpaz, Arlinghaus, Feller: "Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes." in: Blood, Vol. 98, Issue 6, pp. 1773-81, 2001 (PubMed).

Buday, Downward: "Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor." in: Cell, Vol. 73, Issue 3, pp. 611-20, 1993 (PubMed).

Egan, Giddings, Brooks, Buday, Sizeland, Weinberg: "Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation." in: Nature, Vol. 363, Issue 6424, pp. 45-51, 1993 (PubMed).