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CD45RO antibody (CD45RO) (Biotin)

Details for Product anti-CD45RO Antibody No. ABIN610095, Supplier: Log in to see
Antigen
Reactivity
Human
201
45
10
10
3
3
2
Host
Mouse
204
Clonality (Clone)
Monoclonal ()
Conjugate
This CD45RO antibody is conjugated to Biotin
21
19
6
6
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
180
78
73
60
55
49
48
42
37
6
4
3
1
1
1
Options
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Immunogen Cultured human T cell line-CA-1.
Clone UCHL1
Isotype IgG2a
Specificity CD45RO isoform of about 180 kd.
Purification Protein A purified
Alternative Name CD45RO
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Approved: Flo, IHC-P

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer 50 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at +4°C. DO NOT FREEZE.
Product cited in: Furuta, Miura, Copeland, Shang, Oshima, Kamata: "Light Chain 3 associates with a Sos1 guanine nucleotide exchange factor: its significance in the Sos1-mediated Rac1 signaling leading to membrane ruffling." in: Oncogene, Vol. 21, Issue 46, pp. 7060-6, 2002 (PubMed).

Kardinal, Konkol, Lin, Eulitz, Schmidt, Estrov, Talpaz, Arlinghaus, Feller: "Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes." in: Blood, Vol. 98, Issue 6, pp. 1773-81, 2001 (PubMed).

Buday, Downward: "Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor." in: Cell, Vol. 73, Issue 3, pp. 611-20, 1993 (PubMed).

Egan, Giddings, Brooks, Buday, Sizeland, Weinberg: "Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation." in: Nature, Vol. 363, Issue 6424, pp. 45-51, 1993 (PubMed).