CD45RO (CD45RO) antibody (FITC)

Antigen: CD45RO (CD45RO)

Clonality: Monoclonal (UCHL1)

Host: Mouse

Reactivity: Human

Conjugate: FITC

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN610096

Additional Information

Alternative name: CD45RO

Immunogen: Cultured human T cell line-CA-1.

Isotype: IgG2a

Clone: UCHL1

Description: Gene: CD45RO

Specificity: CD45RO isoform of about 180 kd.

Application Details

Application Notes: Flo, IHC-P

Purification: Protein A Column

Buffer: 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5% Glycerol, 0.2% BSA, 0.04% sodium azide

Storage: Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.

Research Area: CD Antigens, Surface Receptors of Immune Cells

Restrictions: For Research Use only

Publications

Product: Egan, Giddings, Brooks et al.: "Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation." in: Nature, Vol. 363, Issue 6424, pp. 45-51, 1993 (PubMed).

Buday, Downward: "Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor." in: Cell, Vol. 73, Issue 3, pp. 611-20, 1993 (PubMed).

Kardinal, Konkol, Lin et al.: "Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes." in: Blood, Vol. 98, Issue 6, pp. 1773-81, 2001 (PubMed).

Furuta, Miura, Copeland et al.: "Light Chain 3 associates with a Sos1 guanine nucleotide exchange factor: its significance in the Sos1-mediated Rac1 signaling leading to membrane ruffling." in: Oncogene, Vol. 21, Issue 46, pp. 7060-6, 2002 (PubMed).