PFKFB2 antibody (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2) (AA 336-385)

Details for Product anti-PFKFB2 Antibody No. ABIN611038, Supplier: Log in to see
Antigen
  • pfkfb2
  • zgc:56282
  • PFK-2/FBPase-2
  • 4930568D07Rik
  • RH2K
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • pfkfb2a
  • PFKFB2
  • pfkfb2
  • Pfkfb2
Alternatives
anti-Human PFKFB2 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 336-385
29
13
8
5
3
2
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Dog (Canine), Horse (Equine), Human, Monkey, Mouse (Murine), Rat (Rattus), Zebrafish
93
52
39
9
7
5
3
3
3
1
1
1
1
1
Host
Rabbit
86
8
3
Clonality
Polyclonal
Conjugate
This PFKFB2 antibody is un-conjugated
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
73
39
30
19
13
4
4
3
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Synthetic peptide located between aa336-385 of mouse Pfkfb2 (Q6GTL7, NP_032851). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Horse, Opossum, Turkey, Zebra finch, Chicken, Platypus (100%), Bovine, Bat, Rabbit, Pig, Guinea pig, Xenopus (92%), Zebrafish (85%).

Type of Immunogen: Synthetic peptide
Specificity Mouse PFKFB2
Predicted Reactivity Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Horse, Chicken (100%) Bovine, Rabbit, Pig (92%) Zebrafish (85%).
Purification Immunoaffinity purified
Alternative Name PFKFB2 (PFKFB2 Antibody Abstract)
Background Name/Gene ID: PFKFB2

Synonyms: PFKFB2, 6PF-2-K/Fru-2,6-P2ase 2, PFK-2/FBPase-2, PFK/FBPase 2, PFKFB, cardiac
Gene ID 5208
NCBI Accession NP_032851
UniProt O60825
Research Area Cancer, Metabolism
Pathways PI3K-Akt Signaling, Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
Application Notes Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Distilled water
Concentration Lot specific
Buffer Lyophilized from PBS with 2 % sucrose
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Supplier Images
 image for anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 336-385) antibody (ABIN611038) anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 336-385) antibody
Product cited in: Jaiswal, Marlow, Gupta, Narayan: "Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells." in: Oncogene, Vol. 21, Issue 55, pp. 8414-27, 2002 (PubMed).

Background publications Duriez, Shah: "Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell death." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 75, Issue 4, pp. 337-49, 1998 (PubMed).

Cherney, McBride, Chen, Alkhatib, Bhatia, Hensley, Smulson: "cDNA sequence, protein structure, and chromosomal location of the human gene for poly(ADP-ribose) polymerase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 23, pp. 8370-4, 1988 (PubMed).

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