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Immunity-Related GTPase Family, Cinema (IRGC) (AA 73-122) antibody

Details for Product No. ABIN611090, Supplier: Log in to see
Antigen
  • IFGGE
  • CINEMA
  • IRGC1
  • Iigp5
  • R30953_1
  • Ifgge
  • Irgc1
  • RGD1311107
  • F630044M05Rik
  • Gm1102
  • Gm474
  • Irgc
  • immunity-related GTPase family, cinema
  • immunity-related GTPase family, cinema 1
  • IRGC
  • Irgc
  • Irgc1
Epitope
AA 73-122
15
14
10
9
7
7
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
57
34
20
Host
Rabbit
57
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
39
36
13
13
10
8
7
3
2
Options
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Immunogen Synthetic peptide located between aa73-122 of mouse Irgc1 (Q8C262, NP_950178). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Rat, Elephant, Panda, Dog (100%), Galago, Marmoset, Bovine, Bat, Horse, Pig, Guinea pig (92%).

Type of Immunogen: Synthetic peptide
Specificity Mouse IRGC
Predicted Reactivity Percent identity by BLAST analysis: Mouse (100%).
Purification Immunoaffinity purified
Alternative Name IRGC1 / CINEMA
Background Name/Gene ID: IRGC

Synonyms: IRGC, CINEMA, Iigp5, IFGGE, Interferon inducible GTPase 5, IRGC1, Interferon-inducible GTPase 5, R30953_1
Gene ID 56269
NCBI Accession NP_950178
UniProt Q6NXR0
Application Notes Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Distilled water
Concentration Lot specific
Buffer Lyophilized from PBS with 2 % sucrose
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Supplier Images
 image for anti-Immunity-Related GTPase Family, Cinema (IRGC) (AA 73-122) antibody (ABIN611090) anti-Immunity-Related GTPase Family, Cinema (IRGC) (AA 73-122) antibody
Product cited in: Bolton, Anthony, Perry: "Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo." in: Neuroscience, Vol. 86, Issue 4, pp. 1245-57, 1998 (PubMed).

Fanning, Jameson, Jesaitis, Anderson: "The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton." in: The Journal of biological chemistry, Vol. 273, Issue 45, pp. 29745-53, 1998 (PubMed).

Ando-Akatsuka, Saitou, Hirase, Kishi, Sakakibara, Itoh, Yonemura, Furuse, Tsukita: "Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues." in: The Journal of cell biology, Vol. 133, Issue 1, pp. 43-7, 1996 (PubMed).