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alpha 1b Adrenergic Receptor antibody (Adrenergic, alpha-1B-, Receptor) (AA 388-437)

Details for Product anti-ADRA1B Antibody No. ABIN611327, Supplier: Log in to see
Antigen
  • LOC100136712
  • [a]1b
  • ADRA1
  • ALPHA1BAR
  • RDC5
  • alpha-1B adrenoceptor
  • adrenergic, alpha-1B-, receptor
  • adrenoceptor alpha 1B
  • adrenergic receptor, alpha 1b
  • LOC100136712
  • ADRA1B
  • Adra1b
Alternatives
anti-Human alpha 1b Adrenergic Receptor antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 388-437
27
18
17
15
11
10
6
4
3
2
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Hamster, Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
124
47
42
9
8
7
7
6
4
3
3
2
1
1
1
Host
Rabbit
108
15
1
Clonality
Polyclonal
Conjugate
This alpha 1b Adrenergic Receptor antibody is un-conjugated
6
6
6
5
5
5
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
78
61
29
22
13
7
3
2
2
1
Options
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Immunogen Synthetic peptide located between aa388-437 of human ADRA1B (P35368, NP_000670). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Dog, Bovine, Rabbit, Pig, Opossum, Guinea pig, Platypus (100%), Bat (92%).

Type of Immunogen: Synthetic peptide
Specificity Human ADRA1B
Predicted Reactivity Percent identity by BLAST analysis: Mouse, Rat, Bovine, Rabbit, Guinea pig (100%).
Purification Immunoaffinity purified
Alternative Name ADRA1B (ADRA1B Antibody Abstract)
Background Name/Gene ID: ADRA1B
Subfamily: Adrenergic
Family: GPCR

Synonyms: ADRA1B, Alpha 1b, Alpha-1B adrenergic receptor, Alpha-1b-adrenergic, Alpha-1B-adrenergic receptor, Alpha1b, Adrenoceptor alpha 1B, Alpha-1B adrenoreceptor, Alpha1B-AR, Alpha1beta-AR, ALPHA1BAR, ADRA1, Alpha-1B adrenoceptor, Alpha1b-adrenergic
Gene ID 147
NCBI Accession NP_000670
UniProt P35368
Pathways AMPK Signaling, Carbohydrate Homeostasis
Application Notes Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Distilled water
Concentration Lot specific
Buffer Lyophilized from PBS with 2 % sucrose
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Supplier Images
 image for anti-alpha 1b Adrenergic Receptor antibody (Adrenergic, alpha-1B-, Receptor) (AA 388-437) (ABIN611327) anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (AA 388-437) antibody
Product cited in: Mirski, Gerlach, Cole: "Sequence determinants of nuclear localization in the alpha and beta isoforms of human topoisomerase II." in: Experimental cell research, Vol. 251, Issue 2, pp. 329-39, 1999 (PubMed).

Brown, Holden, Rahn, Perkins: "Immunohistochemical staining for DNA topoisomerase IIa in Hodgkin's disease." in: American journal of clinical pathology, Vol. 109, Issue 1, pp. 39-44, 1998 (PubMed).

Herzog, Holmes, Tuschong, Ganapathi, Zwelling: "Absence of topoisomerase IIbeta in an amsacrine-resistant human leukemia cell line with mutant topoisomerase IIalpha." in: Cancer research, Vol. 58, Issue 23, pp. 5298-300, 1998 (PubMed).

Background publications Tsai-Pflugfelder, Liu, Liu, Tewey, Whang-Peng, Knutsen, Huebner, Croce, Wang: "Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 19, pp. 7177-81, 1988 (PubMed).