CD9 (CD9) antibody (PE)

Details for Product No. ABIN614778
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Antigen
Synonyms Tspan29, BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29
Reactivity
Mouse (Murine)
(234), (76), (39), (34), (30), (23), (14), (13), (12), (6), (2), (1), (1)
Host
Rat
(175), (69), (40)
Clonality (Clone)
Monoclonal ()
Conjugate
PE
(36), (29), (23), (7), (6), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(211), (116), (48), (46), (39), (34), (33), (30), (21), (19), (10), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN614778
308.00 $
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Immunogen Permeabilized murine bone marrow-derived mast cells (BMMC)
Clone EM-04
Isotype IgG1
Specificity This antibody recognizes CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
Alternative Name CD9
Background CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.
Alternate names: 5H9 antigen, Cell growth-inhibiting gene 2 protein, GIG2, Leukocyte antigen MIC3, MIC3, Motility-related protein, TSPAN29, Tetraspanin-29, p24
Gene ID 12527
NCBI Accession NP_031683
UniProt P40240
Research Area Embryogenesis, Embryonic stem cells, Reproduction, CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE! This product is photosensitive and should be protected from light.
Storage 4 °C
Expiry Date 12 months
Supplier Images
anti-CD9 (CD9) antibody (PE) anti-CD9 (CD9) antibody (PE)
Background publications Schmidt, Künemund, Wintergerst et al.: "CD9 of mouse brain is implicated in neurite outgrowth and cell migration in vitro and is associated with the alpha 6/beta 1 integrin and the neural adhesion molecule L1." in: Journal of neuroscience research, Vol. 43, Issue 1, pp. 12-31, 1996 (PubMed).

Le Naour, Rubinstein, Jasmin et al.: "Severely reduced female fertility in CD9-deficient mice." in: Science (New York, N.Y.), Vol. 287, Issue 5451, pp. 319-21, 2000 (PubMed).

Liu, Cao, Yang et al.: "Tetraspanin CD9 regulates invasion during mouse embryo implantation." in: Journal of molecular endocrinology, Vol. 36, Issue 1, pp. 121-30, 2006 (PubMed).

Unternaehrer, Chow, Pypaert et al.: "The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 1, pp. 234-9, 2007 (PubMed).

Kotha, Zhang, Longhurst et al.: "Functional relevance of tetraspanin CD9 in vascular smooth muscle cell injury phenotypes: a novel target for the prevention of neointimal hyperplasia." in: Atherosclerosis, Vol. 203, Issue 2, pp. 377-86, 2009 (PubMed).

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