PPP4C antibody (C-Term)

Catalog No. ABIN614985

Product Details anti-PPP4C Antibody

Target: PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))

Binding Specificity: C-Term

Reactivity: Human, Rat, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This PPP4C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: C-PQETRGIPSK KP

Specificity: This antibody detects PPP4C.

Cross-Reactivity (Details): Species reactivity (expected):Cow, Dog, Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Peptide from the C-term of the protein sequence according to NP_002711.1 Genename: PPP4C

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3 containing 0.02 % sodium azide as preservative and 0.5 % bovine serum albumin as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PPP4C

Target: PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))

Alternative Name: PPP4C (PPP4C Products)

Synonyms: pp4 antibody, ppx antibody, pp4c antibody, pph3 antibody, MGC75928 antibody, PP4C-A antibody, gc:56413 antibody, ppp4c antibody, wu:fd05e08 antibody, zgc:56413 antibody, PP4 antibody, PP4C antibody, PPH3 antibody, PPP4 antibody, PPX antibody, 1110002D08Rik antibody, AU016079 antibody, Ppx antibody, protein phosphatase 4 catalytic subunit antibody, protein phosphatase 4, catalytic subunit a antibody, protein phosphatase 4, catalytic subunit antibody, protein phosphatase 4 catalytic subunit S homeolog antibody, ppp4c antibody, ppp4ca antibody, PPP4C antibody, Ppp4c antibody, ppp4c.S antibody

Background: Protein phosphatase 4 (protein phosphatase X) is a 35kD serine/threonine phosphatase with predicted binding sites for iron and manganese. It is found in both the cytoplasm and the nucleus. The phophoprotein alpha 4 has been identified as a potential regulatory subunit. PPP4C has been shown to localize to centrosomes/spindle pole bodies and is believed to be involved in microtubule organization. It may also play a role in relaying the TNF-alpha signal to the JNK pathway. Additionally, it has been shown to associate with C-Rel, NF-Kappa B p50, and RelA. Hence, it may be involved in the activation of these key mediators of immune response and apoptosis.Synonyms: PP-X, PP4C, PPP4, PPX, Protein phosphatase X, Serine/threonine-protein phosphatase 4 catalytic subunit

Gene ID: 5531

NCBI Accession: NP_002711

UniProt: P60510