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EIF2S2 antibody (pSer2)
EIF2S2
Reactivity: Human, Mouse
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-EIF2S2 Antibody
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Target
See all EIF2S2 Antibodies
EIF2S2
(Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))
Binding Specificity
All epitopes for EIF2S2 antibodies
pSer2
Reactivity
All reactivities for EIF2S2 antibodies
Human, Mouse
Host
All hosts for EIF2S2 antibodies
Rabbit
Clonality
All clonalities for EIF2S2 antibodies
Polyclonal
Conjugate
All conjugates for EIF2S2 antibodies
This EIF2S2 antibody is un-conjugated
Application
All applications for EIF2S2 antibodies
Western Blotting (WB)
Sequence
M-S(p)-G-D-E
Specificity
This antibody detects endogenous levels of eIF2β only when phosphorylated at serine 2.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse
Purification
Affinity-chromatography using epitope-specific peptide
Immunogen
Peptide sequence around phosphorylation site of serine 2 derived from eIF2beta.
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store (in aliquots) at -20 °C.
Target Details for EIF2S2
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Target
EIF2S2
(Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))
Alternative Name
EIF2B / EIF2S2 (EIF2S2 Products )
Synonyms
EIF2 antibody, EIF2B antibody, EIF2beta antibody, PPP1R67 antibody, eIF-2-beta antibody, 2810026E11Rik antibody, 38kDa antibody, AA408636 antibody, AA571381 antibody, AA986487 antibody, AW822225 antibody, D2Ertd303e antibody, zgc:77084 antibody, wu:fc26g03 antibody, wu:fu10f07 antibody, MGC130959 antibody, DDBDRAFT_0205105 antibody, DDBDRAFT_0234112 antibody, DDB_0205105 antibody, DDB_0234112 antibody, AO090005001412 antibody, eukaryotic translation initiation factor 2 subunit beta antibody, eukaryotic translation initiation factor 2, subunit 2 (beta) antibody, eukaryotic translation initiation factor 2, subunit 2 beta antibody, eukaryotic translation initiation factor 2 subunit beta L homeolog antibody, eIF-3 beta antibody, hypothetical protein antibody, eukaryotic translation initiation factor 2 subunit 2 antibody, EIF2S2 antibody, Eif2s2 antibody, eif2s2 antibody, eif2s2.L antibody, eIF2s2 antibody, TP02_0678 antibody, EDI_093670 antibody, AOR_1_2450174 antibody, MGYG_05853 antibody, PGTG_10708 antibody, LOC101111733 antibody
Background
EIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.Synonyms: Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit beta, eIF-2-beta, eIF2-beta
Molecular Weight
38 kDa
Gene ID
8894
NCBI Accession
NP_003899
UniProt
P20042
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