MAGED1 antibody (C-Term)

Catalog No. ABIN616057

Product Details anti-MAGED1 Antibody

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Binding Specificity: C-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGED1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: C-EAEARAEARN RMGIGDE

Specificity: This antibody detects endogenous level of total Melanoma-associated antigen D1 protein.

Cross-Reactivity (Details): Species reactivity (tested):Mouse, Rat

Purification: Affinity-chromatography using epitope-specific peptide

Immunogen: Peptide with sequence derived from Mouse Melanoma-associated antigen D1.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store (in aliquots) at -20 °C.

Target Details for MAGED1

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Alternative Name: MAGE-D1 (MAGED1 Products)

Synonyms: MAGED1 antibody, DLXIN-1 antibody, NRAGE antibody, 2810433C11Rik antibody, 5430405L04Rik antibody, DXBwg1492e antibody, Dlixin antibody, Dlxin-1 antibody, Dlxin1 antibody, MAGE-D1 antibody, mFLJ00163 antibody, Nrage antibody, MAGE family member D1 antibody, melanoma antigen family D, 1 antibody, melanoma antigen, family D, 1 antibody, MAGED1 antibody, Maged1 antibody

Background: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.Synonyms: MAGE tumor antigen CCF, MAGED1, Melanoma-associated antigen D1, NRAGE, Neurotrophin receptor-interacting MAGE homolog

Molecular Weight: 95 kDa

Gene ID: 94275

NCBI Accession: NP_062765

UniProt: Q9QYH6

Pathways: Neurotrophin Signaling Pathway