OAS2 antibody (N-Term)
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- Target See all OAS2 Antibodies
- OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This OAS2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- OAS2 antibody was raised against the N terminal of OAS2
- Purification
- Affinity purified
- Immunogen
- OAS2 antibody was raised using the N terminal of OAS2 corresponding to a region with amino acids DEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVLFFSDL
- Top Product
- Discover our top product OAS2 Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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OAS2 Blocking Peptide, catalog no. 33R-1912, is also available for use as a blocking control in assays to test for specificity of this OAS2 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of OAS2 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
- Alternative Name
- OAS2 (OAS2 Products)
- Synonyms
- Oasl11 antibody, 2'-5'-oligoadenylate synthetase 2 antibody, 2'-5' oligoadenylate synthetase 2 antibody, 2'-5'-oligoadenylate synthetase 2, 69/71kDa antibody, OAS2 antibody, Oas2 antibody
- Background
- OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.
- Molecular Weight
- 79 kDa (MW of target protein)
- Pathways
- Hepatitis C
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