CXCR2 antibody (N-Term)
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- Target See all CXCR2 Antibodies
- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CXCR2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- IL8 RB antibody was raised against the N terminal of IL8 B
- Purification
- Affinity purified
- Immunogen
- IL8 RB antibody was raised using the N terminal of IL8 B corresponding to a region with amino acids MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYF
- Top Product
- Discover our top product CXCR2 Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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IL8RB Blocking Peptide, catalog no. 33R-5899, is also available for use as a blocking control in assays to test for specificity of this IL8RB antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IL0 B antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
- Alternative Name
- IL8RB (CXCR2 Products)
- Synonyms
- CD182 antibody, CDw128b antibody, CMKAR2 antibody, IL8R2 antibody, IL8RA antibody, IL8RB antibody, CXC-R2 antibody, CXCR-2 antibody, CD128 antibody, CDw128 antibody, Cmkar2 antibody, Gpcr16 antibody, IL-8Rh antibody, IL-8rb antibody, Il8rb antibody, mIL-8RH antibody, C-X-C motif chemokine receptor 2 antibody, chemokine (C-X-C motif) receptor 2 antibody, Cxcr2 antibody, CXCR2 antibody
- Background
- IL8RB is the receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. IL8RB binds to IL-8 with high affinity. IL8RB also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
- Molecular Weight
- 41 kDa (MW of target protein)
- Pathways
- cAMP Metabolic Process
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