TNFRSF10B antibody (N-Term)

Catalog No. ABIN636288

The Rabbit Polyclonal anti-TNFRSF10B antibody (ABIN636288) specifically detects TNFRSF10B. The antibody is reactive with Human samples.

Quick Overview for TNFRSF10B antibody (N-Term) (ABIN636288)

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF10B antibody is un-conjugated

Application: Please inquire

Product Details anti-TNFRSF10B Antibody

Binding Specificity: N-Term

Immunogen: TRAIL receptor 2 antibody was raised in rabbit using N terminus of the human TRAIL-R2 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Serum containing 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for TNFRSF10B

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Alternative Name: TRAIL Receptor 2

Background: TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A distinct receptor for TRAIL, TRAIL-R2 is widely expressed and the gene encoding TRAIL-R2 is located on human chromosome 8p22-21. TRAIL-R2 engages a caspase-dependent apoptotic pathway but, in contrast to TRAIL-R1, TRAIL-R2 mediates apoptosis via the intracellular adaptor molecule FADD/MORT1.

Pathways: p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity