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MC4R antibody

MC4R Reactivity: Human Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN636766
  • Target See all MC4R Antibodies
    MC4R (Melanocortin 4 Receptor (MC4R))
    Reactivity
    • 45
    • 32
    • 29
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 52
    • 1
    Rabbit
    Clonality
    • 53
    Polyclonal
    Conjugate
    • 27
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MC4R antibody is un-conjugated
    Application
    Please inquire
    Cross-Reactivity (Details)
    This 14 AA human MCR42 immunogenic peptide sequence is 100 % identical in monkey, pig, & bovine, 84 % with mouse, and 69 % homologous with rat MC4-R. No significant sequence homology of MCR42 is seen with other melanocortin receptors.
    Purification
    Affinity chromatography purified
    Immunogen
    MC4 R antibody was raised in rabbit using a 14 amino acid peptide of human MC4-R as the immunogen.
    Isotype
    IgG
    Top Product
    Discover our top product MC4R Primary Antibody
  • Application Notes
    Optimal conditions should be determined byt he investigator.
    Restrictions
    For Research Use only
  • Concentration
    Lot specific
    Buffer
    Supplied in 100 mM Tris, pH 7.5, with 0.2 % BSA and 0.05 % NaN3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • Target
    MC4R (Melanocortin 4 Receptor (MC4R))
    Alternative Name
    MC4R (MC4R Products)
    Synonyms
    zMC4 antibody, si:dkey-151m6.62 antibody, mc4r antibody, MC4R antibody, LOC100218148 antibody, Mc4-r antibody, melanocortin 4 receptor antibody, mc4r antibody, MC4R antibody, Mc4r antibody
    Background
    Melanocortin receptor 4 is a protein that in humans is encoded by the MC4R gene. It encodes the MC4 protein, a G-protein coupled receptor that binds alpha-melanocyte stimulating hormone ( alpha-MSH). In murine models MC4 receptors have been found to be involved in feeding behaviour, the regulation of metabolism, sexual behaviour, and male erectile function.
    Pathways
    Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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