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Details for Product No. ABIN638428

CD3 (CD3) antibody

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Antigen
Synonyms CD3
Reactivity
»Alternatives Human
Host
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
Pubmed 8 references available
Catalog no. ABIN638428
Quantity 0.1 mg
Price
290.40 $   Plus shipping costs $45.00
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Availability Will be delivered in 4 to 5 Business Days
Immunogen Human thymocytes, T lymphocytes.
Clone MEM-57
Isotype IgG2a
Specificity The antibody MEM-57 reacts with gamma-epsilon, delta-epsilon dimers of human CD3 complex, a part of a bigger multisubunit T cell receptor complex (CD3/TCR) expressed on peripheral blood T lymphocytes, mature thymocytes.HLDA IV., WS Code T 96
Endotoxin Level low endotoxin
Alternative Name CD3E
Gene ID 916
Restrictions For Research Use only
Buffer Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 micrometer filter sterilized. Endotoxin level is less than 10 EU/mg of the protein, as determined by the LAL test.
Preservative Azide free
Storage 4 °C
Product cited in: Soucek, Chudomel, Hrubá et al.: "Induction of NK and LAK activities in human lymphocyte culture by a cytosol fraction from leukemic myeloblasts and by monoclonal antibody CD 3." in: Neoplasma, Vol. 38, Issue 1, pp. 33-41, 1991 (PubMed).

Horejsí, Angelisová, Bazil et al.: "Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74)." in: Folia biologica, Vol. 34, Issue 1, pp. 23-34, 1988 (PubMed).

Soucek, Hilgert, Budová et al.: "Augmentation of NK cell activity and proliferation in cultured lymphocytes of leukemic patients by monoclonal antibodies CD3 and interleukin-2." in: Neoplasma, Vol. 41, Issue 2, pp. 75-81, 1994 (PubMed).

Hilgert, Franĕk, Stefanová et al.: "Therapeutic in vivo use of the A1-CD3 monoclonal antibody." in: Transplantation, Vol. 55, Issue 2, pp. 435-8, 1993 (PubMed).

Dave, Cao, Browne et al.: "CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage." in: The EMBO journal, Vol. 16, Issue 6, pp. 1360-70, 1997 (PubMed).

Panyi, Bagdány, Bodnár et al.: "Colocalization and nonrandom distribution of Kv1.3 potassium channels and CD3 molecules in the plasma membrane of human T lymphocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2592-7, 2003 (PubMed).

Brdicková, Brdicka, Angelisová et al.: "LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling." in: The Journal of experimental medicine, Vol. 198, Issue 10, pp. 1453-62, 2003 (PubMed).

Drbal, Moertelmaier, Holzhauser et al.: "Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement." in: International immunology, Vol. 19, Issue 5, pp. 675-84, 2007 (PubMed).

Alternatives for antigen "CD3 (CD3)", type "Antibodies"
Hosts (531), (113), (76), (61), (1)
Reactivities (521), (160), (53), (39), (29), (22), (20), (19), (6), (6), (4), (4), (3), (2), (2), (1), (1)
Applications (571), (155), (121), (111), (101), (78), (57), (47), (38), (31), (20), (14), (6), (4), (4), (4), (4), (3), (3), (3), (3), (1), (1), (1), (1)
Conjugates (120), (75), (74), (32), (10), (10), (6), (6), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (30), (13), (11), (10), (6), (6), (4), (3), (3), (2), (1), (1), (1)
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