Add to Basket
Order hotline:
+1 404 474 4654
+1 888 205 9894 (TF)

B-Cell CLL/lymphoma 2 (BCL2) antibody (PE)

Antigen

B-Cell CLL/lymphoma 2 (BCL2)

Synonyms Bcl-2, bcl-2, BCL2
Clonality Monoclonal (Bcl2-100)
Host
Reactivity
Alternatives

Human

Conjugate
Application
Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
5 references available
Catalog no. ABIN638444
Quantity 100 tests
Price 429.00 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 3 to 5 Business Days

Additional Information

Alternative name Bcl2
Gene ID 596
Immunogen Synthetic peptide corresponding to the amino acids 41-54 of human Bcl2
No Cross-Reactivity Mouse (Murine)
Isotype IgG1
Clone Bcl2-100
Specificity The mouse monoclonal antibody Bcl2/100 recognizes Bcl2, a 26 kDa protooncogen with anti-apoptotic effect, expressed in outer mitochondrial membrane, endoplasmic reticulum, nuclear envelope.

Application Details

Buffer The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide, 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.Do not use after expiration date stamped on vial label. Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
Restrictions For Research Use only

Publications

Publications Soilu-Hänninen, Ekert, Bucci et al.: "Nerve growth factor signaling through p75 induces apoptosis in Schwann cells via a Bcl-2-independent pathway." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 12, pp. 4828-38, 1999 (PubMed).

Laflamme, Israël-Assayag, Cormier: "Apoptosis of bronchoalveolar lavage lymphocytes in hypersensitivity pneumonitis." in: The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology, Vol. 21, Issue 2, pp. 225-31, 2003 (PubMed).

Gugasyan, Christou, OReilly et al.: "Bcl-2 transgene expression fails to prevent fatal hepatocyte apoptosis induced by endogenous TNFalpha in mice lacking RelA." in: Cell death and differentiation, Vol. 13, Issue 7, pp. 1235-7, 2006 (PubMed).

Laforge, Petit, Estaquier et al.: "Commitment to apoptosis in CD4(+) T lymphocytes productively infected with human immunodeficiency virus type 1 is initiated by lysosomal membrane permeabilization, itself induced by the isolated expression of the viral protein Nef." in: Journal of virology, Vol. 81, Issue 20, pp. 11426-40, 2007 (PubMed).

Joubert, Marais, Maritz: "Influence of 2-methoxyestradiol on MCF-7 cells: an improved differential interference contrasting technique and Bcl-2 and Bax protein expression levels." in: Biocell : official journal of the Sociedades Latinoamericanas de Microscopía Electronica ... et. al, Vol. 33, Issue 1, pp. 67-70, 2009 (PubMed).

Alternatives

Alternatives for antigen "B-Cell CLL/lymphoma 2 (BCL2)", type "Antibodies"
Hosts Rabbit (124), Mouse (27), Goat (4), Sheep (3)
Reactivities Human (145), Mouse (Murine) (57), Rat (Rattus) (55), Cow (Bovine) (37), Dog (Canine) (37), Pig (Porcine) (34), Rabbit (21), Chicken (18), Horse (Equine) (18), Cat (Feline) (2), Sheep (Ovine) (2)
Applications Western Blotting (WB) (96), Immunofluorescence (IF) (66), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (46), Flow Cytometry (FACS) (42), Immunohistochemistry (IHC) (35), Immunoprecipitation (IP) (35), Immunohistochemistry (Frozen Sections) (IHC (fro)) (26), ELISA (24), Enzyme Immunoassay (EIA) (16), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4), Dot Blot (Dot) (2), Immunocytochemistry (ICC) (2), Immunoelectron Microscopy (IEM) (2)
Conjugates Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitopes pSer70 (5), pThr56 (5), BH3 Domain Specific (1)