TNFRSF1A antibody

Catalog No. ABIN639333

Product Details anti-TNFRSF1A Antibody

Target: TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF1A antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Radioimmunoassay (RIA)

Purpose: Mouse Anti-Human CD120a

Specificity: DS-MB-00283 recognizes an extracellular domain of the 55kD human TNF receptor (p55, TNF-R1, CD120a). No binding occurs to the 75kD TNF receptor (CD120b). CD120a is weakly expressed by monocytes and granulocytes. This product may be used to detect high levels of TNFR1, in western blotting under reducing conditions, such as recombinant material, but it is not suitable for detection of TNFR1 in normal cells in this application. The antibody inhibits the biological activity of both natural and recombinant human TNFalpha and TNFbeta (1-3). Removal of sodium azide is recommended prior to use in functional assays. This product is routinely tested in flow cytometry on human peripheral blood monocytes. This product reacts with Rabbit, Antibody reactivity and working conditions may vary between species.

Characteristics: Adhesion Molecule/Cell Surface

Purification: Purified

Immunogen: Purified human tumour necrosis factor receptor type 1

Isotype: IgG2a

Application Details

Application Notes: ELISA, Flow Cytometry, Radioimmunoassays

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.4

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for TNFRSF1A

Target: TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))

Alternative Name: CD120a (TNFRSF1A Products)

Synonyms: CD120a antibody, FPF antibody, MS5 antibody, TBP1 antibody, TNF-R antibody, TNF-R-I antibody, TNF-R55 antibody, TNFAR antibody, TNFR1 antibody, TNFR1-d2 antibody, TNFR55 antibody, TNFR60 antibody, p55 antibody, p55-R antibody, p60 antibody, TNF-R1 antibody, TNF-alphaR1 antibody, TNFRI antibody, TNFRp55 antibody, TNFalpha-R1 antibody, Tnfr-2 antibody, Tnfr1 antibody, fpf antibody, tbp1 antibody, p55-r antibody, tnf-r antibody, tnfar antibody, tnfr1 antibody, cd120a antibody, tnfr55 antibody, tnfr60 antibody, xtnfr1 antibody, wu:fj65b10 antibody, zgc:85914 antibody, TNFR I antibody, TNFRSF1A antibody, TNFA antibody, cTNF antibody, TNF receptor superfamily member 1A antibody, tumor necrosis factor receptor superfamily, member 1a antibody, TNF receptor superfamily member 1A S homeolog antibody, tumor necrosis factor antibody, TNFRSF1A antibody, Tnfrsf1a antibody, tnfrsf1a.S antibody, tnfrsf1a antibody, TNF antibody

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C, Ubiquitin Proteasome Pathway