MUC1 antibody

Catalog No. ABIN639461

The Mouse Monoclonal anti-MUC1 antibody is suitable to detect MUC1 in samples from Human. It has been validated for WB, ELISA, IHC (p) and IHC (fro).

Quick Overview for MUC1 antibody (ABIN639461)

Target: MUC1 (Mucin 1 (MUC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MUC1 Antibody

Purpose: Mouse Anti-Human MUC1

Specificity: Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. DS-MB-01932 recognizes CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases. DS-MB-01932 reacts with the APDTR peptide sequence (VTSAPDTRPAPGSTAPPAHG) of human CD227.

Characteristics: Cancer-related Markers

Purification: Purified

Immunogen: 60-mer tandem repeat of VTSAPDTRPAPGSTAPPAHG, conjugated to BSA.

Isotype: IgG1

Application Details

Application Notes: Immunohistology - Frozen, ELISA, Immunohistology - Paraffin, Western Blotting

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: CD227

Pathways: Negative Regulation of intrinsic apoptotic Signaling