WNT1 antibody

Catalog No. ABIN640192

Product Details anti-WNT1 Antibody

Target: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit Anti-Human WNT1

Specificity: DS-PB-02787 specifically recognizes Wnt-1, formerly known as int-1, a 343 amino acid non- glycosylated secreted protein associated with the extracellular matrix, involved in normal embryonic development and particularly linked with breast cancer. Wnt-1, which signals through binding to the Frizzled family of transmembrane receptors, was originally identified as a proto-oncogene implicated in carcinomas induced by the mouse mammary tumor virus (MMTV). Wnt-1 belongs to a family of Wnt genes involved in the dorso-ventricular development of the mesoderm during embryogenesis, with a restricted temporal and spatial pattern of expression.

Characteristics: Transcription and its regulation

Purification: Purified

Immunogen: Antisera to human Wnt-1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Isotype: IgG

Application Details

Application Notes: ELISA (dilution: 0.1, 0.2 μg/mL), Immunohistology - Paraffin, Western Blotting

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute with 0.1 mL distilled water.. For long term storage the addition of 0.09 % sodium azide is recommended.

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.2

Storage: -20 °C

Storage Comment: -20°C

Target Details for WNT1

Target: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Alternative Name: WNT-1 (WNT1 Products)

Synonyms: Xint-1 antibody, Xwnt1 antibody, int-1 antibody, int1 antibody, wnt-1 antibody, wnt1-a antibody, Int-1 antibody, Wnt-1 antibody, sw antibody, swaying antibody, BMND16 antibody, INT1 antibody, OI15 antibody, Int1 antibody, WNT-1 antibody, sb:eu647 antibody, zgc:194464 antibody, zgc:194478 antibody, WNT1 antibody, Wnt family member 1 antibody, Wnt family member 1 L homeolog antibody, wingless-type MMTV integration site family, member 1 antibody, WNT1 antibody, wnt1.L antibody, Wnt1 antibody, wnt1 antibody

Pathways: WNT Signaling, Dopaminergic Neurogenesis