CTGF antibody

Catalog No. ABIN641070

Product Details anti-CTGF Antibody

Target: CTGF (Connective Tissue Growth Factor (CTGF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTGF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)

Purpose: Rabbit Anti-Human CTGF

Specificity: DS-PB-02576 specifically recognizes human CTGF (connective tissue growth factor), a 323 amino acid polypeptide and member of the CCN family of secreted cysteine rich regulatory proteins, which is produced by vascular endothelial and umbilical vein cells, and interacts with several other growth factors, including transforming growth factor beta (TGF-beta), vascular endothelial growth factor (VEGF) and bone morphogenetic proteins (BMPs). CTGF is a heparin-binding pleiotropic growth factor involved in chondrogenesis and potentially skeletogenesis. CTGF promotes the adhesion of epithelial cells and fibroblasts, stimulates integrin expression, and also promotes endothelial cell survival, migration and adhesion, implicating CTGF in angiogenesis. CTGF induces extracellular matrix formation, including the deposition of excessive collagen in fibrotic diseases, and has also been implicated in wound healing.

Characteristics: Cytokines/Chemokines/Growth Factors/Receptors

Purification: Purified

Immunogen: Antisera to human CTGF were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Isotype: IgG

Application Details

Application Notes: ELISA (dilution: 0.1, 0.2 μg/mL), Functional Assays, Immunofluorescence, Immunohistology - Paraffin, Western Blotting

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute with 0.1 mL distilled water. For long term storage the addition of 0.09 % sodium azide is recommended. NB: For functional studies do not add azide.

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.2

Storage: -20 °C

Storage Comment: -20°C

Target Details for CTGF

Target: CTGF (Connective Tissue Growth Factor (CTGF))

Alternative Name: CTGF (CTGF Products)

Synonyms: Ccn2 antibody, Fisp12 antibody, Hcs24 antibody, fisp-12 antibody, CCN2 antibody, HCS24 antibody, IGFBP8 antibody, NOV2 antibody, CTGRP antibody, ctgf antibody, hm:zeh1559 antibody, si:dkey-266k12.4 antibody, wu:fl25c03 antibody, zeh1559 antibody, zgc:136644 antibody, XCTGF antibody, ccn2 antibody, nov2 antibody, hcs24 antibody, igfbp8 antibody, CTGF antibody, si:ch211-173b8.2 antibody, connective tissue growth factor antibody, connective tissue growth factor a antibody, connective tissue growth factor L homeolog antibody, connective tissue growth factor b antibody, Ctgf antibody, CTGF antibody, ctgfa antibody, ctgf.L antibody, ctgf antibody, ctgfb antibody

Pathways: Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding