HRK antibody

Catalog No. ABIN644080

Product Details anti-HRK Antibody

Target: HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRK antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human HRK

Specificity: DS-PB-01015 detects Harakiri (HRK), also known as DP5. HRK is a BH3 only protein of the Bcl-2 family, which promotes Bax dependent apoptosis. HRK regulates apoptosis through its interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL, and in conjunction to the mitochondrial pore forming protein p32. HRK is thought to have a specific role in initiating neuronal and haematopoietic cell apoptosis, in particular to growth factor deprivation. Aberrant methylation of HRK is frequently detected in primary colorectal cancers. Despite its predicted molecular weight, HRK often migrates at 12-15kD. reacts with: Rat, Mouse. Antibody reactivity and working conditions may vary between species.

Purification: Purified

Immunogen: Antisera to HRK were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Isotype: IgG

Application Details

Application Notes: Western Blotting

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for HRK

Target: HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))

Alternative Name: HRK (HRK Products)

Synonyms: DP5 antibody, HARAKIRI antibody, AI838259 antibody, Bid3 antibody, harakiri antibody, Dp5 antibody, harakiri, BCL2 interacting protein antibody, harakiri, BCL2 interacting protein (contains only BH3 domain) antibody, HRK antibody, Hrk antibody