CBX3 antibody

Catalog No. ABIN645855

The Goat not_set anti-CBX3 antibody (ABIN645855) specifically detects CBX3. The antibody is reactive with Mouse, Rat and Dog samples.

Quick Overview for CBX3 antibody (ABIN645855)

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Reactivity: Mouse, Rat, Dog

Host: Goat

Conjugate: This CBX3 antibody is un-conjugated

Application: Please inquire

Product Details anti-CBX3 Antibody

Specificity: The Goat anti-HP1 Gamma / CBX3 antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine)

Characteristics: Goat Anti-CBX3 / HP1 gamma

Immunogen: Peptide with sequence C-EAFLNSQKAGKEKD, from the internal region of the protein sequence according to NP_009207.2, NP_057671.2, was used as immunogen.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Storage: -20 °C

Target Details for CBX3

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Alternative Name: CBX3 / HP1 gamma

Background: CBX3 antibody is involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

NCBI Accession: NP_009207