Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CBX3 antibody (AA 1-183)

CBX3 Reactivity: Human WB, IHC, IP, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1512681
  • Target See all CBX3 Antibodies
    CBX3 (Chromobox Homolog 3 (CBX3))
    Binding Specificity
    • 20
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-183
    Reactivity
    • 106
    • 70
    • 54
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    Human
    Host
    • 79
    • 27
    • 2
    Rabbit
    Clonality
    • 71
    • 37
    Polyclonal
    Conjugate
    • 54
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This CBX3 antibody is un-conjugated
    Application
    • 56
    • 31
    • 29
    • 27
    • 27
    • 19
    • 18
    • 14
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Sequence
    MASNKTTLQK MGKKQNGKSK KVEEAEPEEF VVEKVLDRRV VNGKVEYFLK WKGFTDADNT WEPEENLDCP ELIEAFLNSQ KAGKEKDGTK RKSLSDSESD DSKSKKKRDA ADKPRGFARG LDPERIIGAT DSSGELMFLM KWKDSDEADL VLAKEANMKC PQIVIAFYEE RLTWHSCPED EAQ
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-183 of human HP1 gamma/HP1 gamma/CBX3 (NP_009207.2).
    Isotype
    IgG
    Top Product
    Discover our top product CBX3 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CBX3 (Chromobox Homolog 3 (CBX3))
    Alternative Name
    CBX3 (CBX3 Products)
    Synonyms
    HECH antibody, HP1-GAMMA antibody, HP1Hs-gamma antibody, Hp1-gamma antibody, HP1g antibody, M32 antibody, cbx3 antibody, cbx3a antibody, xhp1g antibody, wu:fb61b02 antibody, zgc:153397 antibody, chromobox 3 antibody, chromobox 3 L homeolog antibody, chromobox protein homolog 3 pseudogene antibody, chromobox homolog 3a (HP1 gamma homolog, Drosophila) antibody, CBX3 antibody, Cbx3 antibody, cbx3.L antibody, LOC100355282 antibody, cbx3a antibody
    Background
    At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.,CBX3,HECH,HP1-GAMMA,HP1Hs-gamma,Epigenetics & Nuclear Signaling,CBX3
    Molecular Weight
    20 kDa
    Gene ID
    11335
    UniProt
    Q13185
You are here:
Support