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CBX3 antibody

CBX3 Reactivity: Human, Mouse WB, IHC, IP, ICC Host: Mouse Monoclonal unconjugated
Catalog No. ABIN6241538
  • Target See all CBX3 Antibodies
    CBX3 (Chromobox Homolog 3 (CBX3))
    Reactivity
    • 106
    • 69
    • 54
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    Human, Mouse
    Host
    • 80
    • 26
    • 2
    Mouse
    Clonality
    • 72
    • 36
    Monoclonal
    Conjugate
    • 54
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This CBX3 antibody is un-conjugated
    Application
    • 56
    • 31
    • 29
    • 27
    • 27
    • 19
    • 18
    • 15
    • 7
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Immunogen
    Recombinant Protein
    Top Product
    Discover our top product CBX3 Primary Antibody
  • Application Notes
    IP: 1:500. WB: 1:1000. IHC: 1:100. ICC: 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    4 °C,-20 °C
  • Target
    CBX3 (Chromobox Homolog 3 (CBX3))
    Alternative Name
    HP1-gamma (CBX3 Products)
    Synonyms
    HECH antibody, HP1-GAMMA antibody, HP1Hs-gamma antibody, Hp1-gamma antibody, HP1g antibody, M32 antibody, cbx3 antibody, cbx3a antibody, xhp1g antibody, wu:fb61b02 antibody, zgc:153397 antibody, chromobox 3 antibody, chromobox 3 L homeolog antibody, chromobox protein homolog 3 pseudogene antibody, chromobox homolog 3a (HP1 gamma homolog, Drosophila) antibody, CBX3 antibody, Cbx3 antibody, cbx3.L antibody, LOC100355282 antibody, cbx3a antibody
    Background
    Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the mehtyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.
    UniProt
    Q13185
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