SP1 antibody

Catalog No. ABIN645858

Product Details anti-SP1 Antibody

Target: SP1 (Sp1 Transcription Factor (SP1))

Reactivity: Human

Host: Goat

Conjugate: This SP1 antibody is un-conjugated

Application: Please inquire

Specificity: The Goat Anti-SP1 antibody detects protein derived from human recombinant protein and HELA lysate at various concentrations.

Cross-Reactivity: Human

Characteristics: Goat Anti-SP1

Immunogen: Peptide with sequence CSRIESPNENSNNSQ, from the internal region of the protein sequence according to NP_612482.2, was used as an immunogen.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Storage: -20 °C

Target Details for SP1

Target: SP1 (Sp1 Transcription Factor (SP1))

Alternative Name: SP1 (SP1 Products)

Synonyms: fc18h09 antibody, zgc:85950 antibody, wu:fc18h09 antibody, SP1 antibody, 1110003E12Rik antibody, AA450830 antibody, AI845540 antibody, Sp1-1 antibody, sp1 transcription factor antibody, Sp1 transcription factor antibody, Sp1 transcription factor L homeolog antibody, trans-acting transcription factor 1 antibody, sp1 antibody, SP1 antibody, Sp1 antibody, sp1.L antibody

Background: Sp1 is found in its potential to simultaneously regulate a wide array of genes through changes in its phosphorylation state. Changes in phosphorylation often results in functional changes to Sp1 such as altered DNA binding and/or promoter activation. A number of enzymes act on Sp1, including DNA-PK, protein phosphatases, casein kinase II, ERK and cyclin-dependent kinase. A strong relationship exists between Sp1 phosphorylation state and growth at both the organ and cellular level, for this reason Sp1 has been implicated in oncogenesis.

NCBI Accession: NP_612482

Pathways: Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction