CD163 antibody (FITC)

Catalog No. ABIN6253944

Product Details anti-CD163 Antibody (FITC)

Target: CD163

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD163 antibody is conjugated to FITC

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Fluorescence Microscopy (FM)

Specificity: The CD163 antigen is the cysteine-rich human scavenger receptor protein (p155, M130) found on mononuclear phagocytes, monocytes, and macrophages. CD163 is up-regulated on mononuclear phagocytes by IL-4, IL-6 and dexamethasone and serves as a receptor for the hemoglobin / haptoglobin complex. Expression of CD163 is restricted to cells of monocyte lineage and increases as the monocytes mature into macrophages. CD163 is present on all CD14 + monocytes, most CD64+ monocytes, and demonstrates higher expression on CD16+ monocytes. Stimulation of monocytes and macrophages by lipopolysacharide (LPS), IL-10, and tumor necrosis factor alpha (TNF-α) causes shedding of CD163 from the cell surface into plasma or supernata

Clone: MAC2-158

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C

Target Details for CD163

Target: CD163

Alternative Name: CD163 (CD163 Products)

Synonyms: DMBT1 antibody, CD163 antibody, CD163v2 antibody, CD163v3 antibody, M130 antibody, MM130 antibody, deleted in malignant brain tumors 1 protein-like antibody, CD163 molecule antibody, CD163 antigen antibody, LOC426820 antibody, CD163 antibody, Cd163 antibody

Background: Antigen distribution: The CD163 antigen is the cysteine-rich human scavenger receptor protein (p155, M130) found on mononuclear phagocytes, monocytes, and macrophages. CD163 is up-regulated on mononuclear phagocytes by IL-4, IL-6 and dexamethasone and serves as a receptor for the hemoglobin / haptoglobin complex. Expression of CD163 is restricted to cells of monocyte lineage and increases as the monocytes mature into macrophages. CD163 is present on all CD14 + monocytes, most CD64+ monocytes, and demonstrates higher expression on CD16+ monocytes. Stimulation of monocytes and macrophages by lipopolysacharide (LPS), IL-10, and tumor necrosis factor alpha (TNF-α) causes shedding of CD163 from the cell surface into plasma or supernata. Cellular Expression: Mononuclear phagocytes, monocytes and macrophages.