PSMD7 antibody (C-Term)

Catalog No. ABIN650763

Product Details anti-PSMD7 Antibody

Target: PSMD7 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (PSMD7))

Binding Specificity: AA 267-295, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD7 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PSMD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the C-terminal region of human PSMD7.

Clone: RB20858

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PSMD7

Target: PSMD7 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (PSMD7))

Alternative Name: PSMD7 (PSMD7 Products)

Synonyms: wu:fi03c01 antibody, zgc:55284 antibody, CG3416 antibody, Dmel\\CG3416 antibody, PRSC_DROME antibody, RPN8 antibody, Rpn8 antibody, S12 antibody, l(2)k08003 antibody, p39B antibody, DDBDRAFT_0205949 antibody, DDBDRAFT_0232987 antibody, DDB_0205949 antibody, DDB_0232987 antibody, MOV34 antibody, P40 antibody, AW107203 antibody, Mov-34 antibody, Mov34 antibody, proteasome 26S subunit, non-ATPase 7 antibody, Regulatory particle non-ATPase 8 antibody, 26s proteasome regulatory subunit s12 antibody, 26S proteasome non-ATPase regulatory subunit 7 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 antibody, psmd7 antibody, Rpn8 antibody, PSMD7 antibody, PY05051 antibody, psmD7 antibody, Psmd7 antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD7 is a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

Molecular Weight: 37025

Gene ID: 5713

NCBI Accession: NP_002802

UniProt: P51665

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway