TNFRSF8 antibody (AA 458-487)

Catalog No. ABIN651104

The Rabbit Polyclonal anti-TNFRSF8 antibody is suitable to detect TNFRSF8 in samples from Human and Mouse. It has been validated for WB and IHC (p).

Quick Overview for TNFRSF8 antibody (AA 458-487) (ABIN651104)

Target: TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB15532

Product Details anti-TNFRSF8 Antibody

Binding Specificity: AA 458-487

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNFRSF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-487 amino acids from human TNFRSF8.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TNFRSF8

Target: TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))

Alternative Name: TNFRSF8-Y479

Background: TNFRSF8 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

Molecular Weight: 63747

Gene ID: 943

NCBI Accession: NP_001234, NP_001268359

UniProt: P28908