TNFRSF8 antibody (AA 19-379)

Catalog No. ABIN7193372

The Mouse Monoclonal anti-TNFRSF8 antibody has been validated for FACS and ELISA. It is suitable to detect TNFRSF8 in samples from Human.

Quick Overview for TNFRSF8 antibody (AA 19-379) (ABIN7193372)

Target: TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF8 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Clone: 4D1C2

Product Details anti-TNFRSF8 Antibody

Binding Specificity: AA 19-379

Purpose: CD30 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD30 (AA: 19-379) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TNFRSF8

Target: TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))

Alternative Name: CD30

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Molecular Weight: 63.7 kDa

Gene ID: 943

UniProt: P28908