TBKB1 (N-Term) antibody

Antigen: TBKB1

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN651513

Additional Information

Gene ID: 9755

UniProt: A7MCY6, NP_055541.1

Immunogen: This TBKB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-80 amino acids from the N-terminal region of human TBKB1.

Isotype: Ig

Description: Other names: TANK-binding kinase 1-binding protein 1, TBK1-binding protein 1,KIAA0775, TBKBP1

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This TBKB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-80 amino acids from the N-terminal region of human TBKB1.

Molecular Weight: 67702  DA

Comments:

Background: TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway

Application Details

Application Notes: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Images

TBKB1 Antibody (N-term) (ABIN651513) western blot analysis in mouse cerebellum tissue lysates (35ug/lane). This demonstrates the TBKB1 antibody detected TBKB1 protein (arrow).

Publications

Product: Bouwmeester, Bauch, Ruffner et al.: "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway." in: Nature cell biology, Vol. 6, Issue 2, pp. 97-105, 2004 (PubMed).

Ryzhakov, Randow: "SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK." in: The EMBO journal, Vol. 26, Issue 13, pp. 3180-90, 2007 (PubMed).