TBKBP1 antibody (C-Term)

Catalog No. ABIN1881872

Product Details anti-TBKBP1 Antibody

Target: TBKBP1 (TBK1 Binding Protein 1 (TBKBP1))

Binding Specificity: AA 470-497, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBKBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Tbkbp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-497 amino acids from the C-terminal region of mouse Tbkbp1.

Clone: RB42418

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-TBKBP1 antibody (ABIN1881872)

Ryzhakov, Randow: "SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK." in: The EMBO journal, Vol. 26, Issue 13, pp. 3180-90, (2007) (PubMed).

Zambrowicz, Abuin, Ramirez-Solis, Richter, Piggott, BeltrandelRio, Buxton, Edwards, Finch, Friddle, Gupta, Hansen, Hu, Huang, Jaing, Key, Kipp, Kohlhauff, Ma, Markesich, Payne, Potter, Qian, Shaw et al.: "Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14109-14, (2003) (PubMed).

Target Details for TBKBP1

Target: TBKBP1 (TBK1 Binding Protein 1 (TBKBP1))

Alternative Name: Tbkbp1 (TBKBP1 Products)

Synonyms: TBKBP1 antibody, ProSAPiP2 antibody, SINTBAD antibody, 3110043L15Rik antibody, Prosapip2 antibody, TBK1 binding protein 1 antibody, TBKBP1 antibody, Tbkbp1 antibody

Background: Adapter protein which constitutively binds TBK1 and IKBKE and may play a role in antiviral innate immunity. Essential for the efficient induction of IRF-dependent transcription following infection with Sendai virus.

Molecular Weight: 67001

NCBI Accession: NP_932768

UniProt: A2A9T0

Pathways: SARS-CoV-2 Protein Interactome