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TBKBP1 antibody (C-Term)

TBKBP1 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500543
  • Target See all TBKBP1 Antibodies
    TBKBP1 (TBK1 Binding Protein 1 (TBKBP1))
    Binding Specificity
    • 13
    • 8
    • 8
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 26
    • 25
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 38
    Rabbit
    Clonality
    • 38
    Polyclonal
    Conjugate
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    This TBKBP1 antibody is un-conjugated
    Application
    • 34
    • 27
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Prosapip2.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    Prosapip2 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Prosapip2.
    Isotype
    IgG
    Top Product
    Discover our top product TBKBP1 Primary Antibody
  • Application Notes
    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    TBKBP1 (TBK1 Binding Protein 1 (TBKBP1))
    Alternative Name
    TBKBP1 (TBKBP1 Products)
    Synonyms
    TBKBP1 antibody, ProSAPiP2 antibody, SINTBAD antibody, 3110043L15Rik antibody, Prosapip2 antibody, TBK1 binding protein 1 antibody, TBKBP1 antibody, Tbkbp1 antibody
    Background
    Prosapip2 (TBKBP1) is essential for signal transduction during viral infection thus plays a major role in the TNF/NF-kappaB pathway. It is an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE and may play a role in antiviral innate immunity. Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains which are linked to each other by interchain disulfide bonds. It has a ubiquitous expression with highest levels in ovary, followed by the neuronal system. Prosapip2 binds to TBK1 and helps in the activation of IRF3 which controls the expression of antiviral genes during infection. Recent studies show that Prosapip2 is an interaction partner of ProSAP2/Shank3 and actin, suggesting a role as a linker molecule between postsynaptic density and the cytoskeleton.Synonyms: KIAA0775, ProSAPiP2, Sintbad, TANK-binding kinase 1-binding protein 1, TBK1-binding protein 1
    Gene ID
    9755
    NCBI Accession
    NP_055541
    UniProt
    A7MCY6
    Pathways
    SARS-CoV-2 Protein Interactome
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