Histone Cluster 1, H2ak (HIST1H2AK) (N-Term), (AA 1-30) antibody

Details for Product No. ABIN651540
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Antigen
Epitope
N-Term, AA 1-30
(6), (6)
Reactivity
Human
(6)
Host
Rabbit
(6)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(6), (6)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN651540
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Immunogen This HIST1H2AK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human HIST1H2AK.
Clone RB26883
Isotype Ig
Specificity This HIST1H2AK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2AK.
Predicted Reactivity Cow (Bovine),Chicken,Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HIST1H2AK
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.
Synonyms: Histone H2A/p, Histone H2A type 1, H2A.1,H2AFP, HIST1H2AG
Molecular Weight 14091  DA
Gene ID 8330
NCBI Accession NP_003501
UniProt P0C0S8
Research Area Ubiquitin-related antibodies, Signaling, Protein Modifications, Transcription Factors, Chromatin
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Histone Cluster 1, H2ak (HIST1H2AK) (N-Term), (AA 1-30) antibody HIST1H2AK Antibody (N-term) (ABIN651540) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the HIST1H2AK antibody detected the HIST1H2AK protein (arrow).
Background publications Bergink, Salomons, Hoogstraten et al.: "DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A." in: Genes & development, Vol. 20, Issue 10, pp. 1343-52, 2006 (PubMed).

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