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Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 148-176), (C-Term) antibody

Details for Product No. ABIN651855, Supplier: Log in to see
Antigen
  • adcyap1
  • GRF-PACAP
  • zgc:103760
  • xx:af217251
  • pac1
  • pacapr
  • pacapri
  • pacap
  • ADCYAP1
  • PACAP
  • Pacap
  • grf
  • MEDA-7
  • pERp1
  • RGD1310251
  • 2010001M09Rik
  • AV064572
Alternatives
anti-Human Adenylate Cyclase Activating Polypeptide 1 (Pituitary) antibody for Enzyme Immunoassay
Epitope
AA 148-176, C-Term
31
19
13
8
6
6
5
3
1
1
1
Reactivity
Human
102
36
28
12
3
3
3
1
Host
Rabbit
91
14
9
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
7
5
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
57
43
26
19
13
11
9
8
7
3
1
Supplier
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Immunogen This ADCYAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 AA from the C-terminal region of human ADCYAP1.
Clone RB21605
Isotype Ig
Specificity This ADCYAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-176 amino acids from the C-terminal region of human ADCYAP1.
Predicted Reactivity Mouse (Murine),Pig (Porcine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ADCYAP1 (ADCYAP1 Antibody Abstract)
Background ADCYAP1 is adenylate cyclase activating polypeptide 1. Mediated by adenylate cyclase activating polypeptide 1 receptors, this polypeptide stimulates adenylate cyclase and subsequently increases the cAMP level in target cells. Adenylate cyclase activating polypeptide 1 is not only a hypophysiotropic hormone, but also functions as a neurotransmitter and neuromodulator. In addition, it plays a role in paracrine and autocrine regulation of certain types of cells. This gene encodes three different mature peptides, including two isotypes, a shorter form and a longer form.
Synonyms: Pituitary adenylate cyclase-activating polypeptide,ADCYAP1,
Molecular Weight 18835 DA
Gene ID 116
NCBI Accession NP_001093203
UniProt P18509
Research Area Signaling, Cell Signaling, Protein Modifications, Cell Structure
Pathways Neurotrophin Signaling Pathway
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.33 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 148-176), (C-Term) antibody (ABIN651855) ADCYAP1 Antibody (C-term) (ABIN651855) western blot analysis in 293 cell line lysates...
Immunohistochemistry (IHC) image for anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 148-176), (C-Term) antibody (ABIN651855) ADCYAP1 Antibody (C-term) (ABIN651855) immunohistochemistry analysis in formalin fixe...
Flow Cytometry (FACS) image for anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 148-176), (C-Term) antibody (ABIN651855) ADCYAP1 Antibody (C-term) (ABIN651855) flow cytometric analysis of 293 cells (right h...
Background publications Kimura, Ohkubo, Ogi et al.: "A novel peptide which stimulates adenylate cyclase: molecular cloning and characterization of the ovine and human cDNAs." in: Biochemical and biophysical research communications, Vol. 166, Issue 1, pp. 81-9, 1990 (PubMed).

Ohkubo, Kimura, Ogi et al.: "Primary structure and characterization of the precursor to human pituitary adenylate cyclase activating polypeptide." in: DNA and cell biology, Vol. 11, Issue 1, pp. 21-30, 1992 (PubMed).

Hosoya, Kimura, Ogi et al.: "Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene." in: Biochimica et biophysica acta, Vol. 1129, Issue 2, pp. 199-206, 1992 (PubMed).