|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Kallikrein 6 (KLK6) (N-Term) antibody
|Synonyms||hK6, Bssp, Klk7, SP59, ZYME, PRSS9, PRSS18, MGC9355, NEUROSIN, rk8, KLK8, Klk6, rGK-8, Klk1c8, klk6, Prss9|
Alternatives Western Blotting (WB), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This KLK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6~35 amino acids from the N-terminal region of human KLK6.|
|Description||Other names: Protease M, Neurosin, Zyme, SP59,|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This Kallikrein 6 Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6~35 amino acids from the N-terminal region of human KLK6.|
|Molecular Weight||26856 DA|
Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
|Application Notes||The suggested dilution is: ELISA~~1:1,000 Western blotting~~1:50~100|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca|
|Research Area||Neurology, Cell Structure|
|Restrictions||For Research Use only|
Sauter, Lininger, Magklara et al.: "Association of kallikrein expression in nipple aspirate fluid with breast cancer risk." in: International journal of cancer. Journal international du cancer, Vol. 108, Issue 4, pp. 588-91, 2003 (PubMed).
Pampalakis, Kurlender, Diamandis et al.: "Cloning and characterization of novel isoforms of the human kallikrein 6 gene." in: Biochemical and biophysical research communications, Vol. 320, Issue 1, pp. 54-61, 2004 (PubMed).
Ghosh, Grass, Soosaipillai et al.: "Human kallikrein 6 degrades extracellular matrix proteins and may enhance the metastatic potential of tumour cells." in: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, Vol. 25, Issue 4, pp. 193-9, 2004 (PubMed).
|Hosts||Rabbit (25), Goat (4), Mouse (3)|
|Reactivities||Human (28), Mouse (Murine) (21), Rat (Rattus) (19), Cow (Bovine) (1), Dog (Canine) (1)|
|Applications||Immunofluorescence (IF) (15), Western Blotting (WB) (15), ELISA (12), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (DB) (2), Cellular Assay (CA) (1), Dot Blot (Dot) (1), Immunoassay (IA) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1), Immunostaining (ISt) (1)|
|Conjugates||Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)|
|Epitopes||AA 23-240 (1), C-Term (1), Center (1), N-Term (1)|