DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39A (DDX39) (AA 250-277), (Center), (Tyr265) antibody

Details for Product No. ABIN652341
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Antigen
Epitope
AA 250-277, Center, Tyr265
(2), (2), (1), (1), (1), (1)
Reactivity
Human
(18), (4), (3), (1), (1), (1), (1)
Host
Rabbit
(16), (4)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB)
(17), (5), (5), (4), (3), (3), (3), (3), (2), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN652341
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Immunogen This DDX39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-277 AA from the Central region of human DDX39.
Clone RB17938
Isotype Ig
Specificity This DDX39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256~286 amino acids from the Central region of human DDX39.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name DDX39
Background DDX39 is a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.
Synonyms: ATP-dependent RNA helicase DDX39, DEAD box protein 39, Nuclear RNA helicase URH49,
Molecular Weight 49130 DA
Gene ID 10212
UniProt O00148
Research Area Translation Factors, Cancer, Signaling, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39A (DDX39) (AA 250-277), (Center), (Tyr265) antibody Western blot analysis of DDX39 Antibody (Center Y265) (ABIN652341) in HepG2 cell line lysates (35 µg/lane). DDX39 (arrow) was detected using the purified polyclonal antibody.
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39A (DDX39) (AA 250-277), (Center), (Tyr265) antibody (2) Western blot analysis of DDX39 (arrow) using rabbit polyclonal DDX39 Antibody (Center Y265) (ABIN652341). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DDX39 gene.
Background publications Lehner, Semple, Brown et al.: "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region." in: Genomics, Vol. 83, Issue 1, pp. 153-67, 2003 (PubMed).

Pryor, Tung, Yang et al.: "Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56." in: Nucleic acids research, Vol. 32, Issue 6, pp. 1857-65, 2004 (PubMed).

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