DDX39 antibody (N-Term)

Catalog No. ABIN2775205

There is 1 publication for this product available. The Rabbit Polyclonal anti-DDX39 antibody is suitable to detect DDX39 in samples from Human, Mouse, Rat, Cow, Dog and Guinea Pig. It has been validated for WB.

Quick Overview for DDX39 antibody (N-Term) (ABIN2775205)

Target: DDX39 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39A (DDX39))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX39 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DDX39 Antibody

Binding Specificity: N-Term

Purpose: DDX39 Antibody - N-terminal region

Sequence: MAEQDVENDL LDYDEEEEPQ APQESTPAPP KKDIKGSYVS IHSSGFRDFL

Predicted Reactivity: Cow: 77%, Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against DDX39. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDX39

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8098617

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-DDX39 antibody (ABIN2775205)

Majerciak, Deng, Zheng: "Requirement of UAP56, URH49, RBM15, and OTT3 in the expression of Kaposi sarcoma-associated herpesvirus ORF57." in: Virology, Vol. 407, Issue 2, pp. 206-12, (2010) (PubMed).

Target Details for DDX39

Target: DDX39 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39A (DDX39))

Alternative Name: DDX39

Background:

Background Information: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX39 encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants encoding different isoforms.

Gene Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A

Alternative Symbols: BAT1, DDXL, BAT1L, DDX39, URH49

Protein Name: ATP-dependent RNA helicase DDX39A

Molecular Weight: 47kDa

Gene ID: 10212

NCBI Accession: NP_005795

UniProt: O00148