anti-Vitronectin antibody (VTN) (AA 65-93)

Details for Product anti-VTN Antibody No. ABIN652347
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Antigen
Synonyms VTN, DKFZp470F0511, LOC100228142, vtn, zgc:112277, V75, VN, VNT, AI256434, Vn, Aa1018
Epitope
AA 65-93, N-Term
(18), (12), (12), (11), (8), (8), (6), (5), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(269), (67), (24), (15), (6), (3), (3), (3), (3), (1)
Host
Rabbit
(183), (123), (17), (2), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
This Vitronectin antibody is un-conjugated
(18), (17), (15), (7), (7), (7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(259), (197), (89), (36), (33), (24), (24), (21), (18), (16), (10), (10), (10), (10), (9), (8), (5), (5), (4), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
Quantity 400 μL
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Immunogen This VTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-93 AA from the N-terminal region of human VTN.
Clone RB17843
Isotype Ig
Specificity This VTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72~101 amino acids from the N-terminal region of human VTN.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name VTN (VTN Antibody Abstract)
Background VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Synonyms: Vitronectin, Serum-spreading factor, S-protein, V75, Vitronectin V65 subunit, Vitronectin V10 subunit, Somatomedin-B , VTN
Pathways: Focal adhesion, ECM-receptor interaction
Molecular Weight 54,306 Da
Gene ID 7448
UniProt P04004
Research Area Signaling, Cancer
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.34 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Vitronectin (VTN) (AA 65-93), (N-Term) antibody Western blot analysis of VTN Antibody (N-term) (ABIN652347) in NCI-H460 cell line lys...
anti-Vitronectin (VTN) (AA 65-93), (N-Term) antibody (2) Formalin-fixed and paraffin-embedded human lung carcinoma reacted with VTN Antibody (...
anti-Vitronectin (VTN) (AA 65-93), (N-Term) antibody (3) VTN Antibody (N-term) (ABIN652347) flow cytometric analysis of NCI-H460 cells (bottom...
Background publications Sigurdardottir, Wiman: "Identification of a PAI-1 binding site in vitronectin." in: Biochimica et biophysica acta, Vol. 1208, Issue 1, pp. 104-10, 1994 (PubMed).

Jenne, Stanley: "Molecular cloning of S-protein, a link between complement, coagulation and cell-substrate adhesion." in: The EMBO journal, Vol. 4, Issue 12, pp. 3153-7, 1986 (PubMed).

Seiffert, Loskutoff: "Evidence that type 1 plasminogen activator inhibitor binds to the somatomedin B domain of vitronectin." in: The Journal of biological chemistry, Vol. 266, Issue 5, pp. 2824-30, 1991 (PubMed).

Validation Images
Catalog No. ABIN652347
291.50 $
Plus shipping costs $45.00
Quantity
Price
400 μL
291.50 $

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