|+1 404 474 4654|
|+1 888 205 9894 (TF)|
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (Center) antibody
|Synonyms||BAM, BIM, BOD, BimL, BimEL, BIM-beta6, BIM-beta7, BIM-alpha6, Bim, Bod, 1500006F24Rik, bim|
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA
|2 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This BCL2L11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140~169 amino acids from the Center region of human BCL2L11.|
|Description||Other names: Bcl-2-like protein 11, Bcl2-L-11, Bcl2-interacting mediator of cell death, BIM, BCL2L11|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This BCL2L11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140~169 amino acids from the Center region of human BCL2L11.|
|Molecular Weight||22171 DA|
Background: BCL2L11 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Flow cytometric~~1:10~50|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Apoptosis/Necrosis, Neurology|
|Restrictions||For Research Use only|
Putcha, Le, Frank et al.: "JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis." in: Neuron, Vol. 38, Issue 6, pp. 899-914, 2003 (PubMed).
Hippe, Weber, Zhou et al.: "Toxoplasma gondii infection confers resistance against BimS-induced apoptosis by preventing the activation and mitochondrial targeting of pro-apoptotic Bax." in: Journal of cell science, Vol. 122, Issue Pt 19, pp. 3511-21, 2009 (PubMed).