BIM antibody (pSer69)

Catalog No. ABIN7300420

The Rabbit Polyclonal anti-BIM antibody is suitable to detect BIM in samples from Human, Mouse, Rat, Cow and Sheep. It has been validated for WB, IHC and IF.

Quick Overview for BIM antibody (pSer69) (ABIN7300420)

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reactivity: Human, Mouse, Rat, Cow, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BIM Antibody

Binding Specificity: pSer69

Purpose: Rabbit polyclonal antibody to BIM (Phospho-S69)

Specificity: Recognizes endogenous levels of BIM protein only when phosphorylated at S69.

Characteristics: Rabbit polyclonal antibody to BIM (pS69)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S69 of human BIM protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BIM

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Alternative Name: BIM

Background: BIM, Bcl-2-like protein 11, Bcl2-L-11, Bcl2-interacting mediator of cell death

Gene ID: 10018, 12125, 64547

UniProt: O43521

Pathways: PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity