MAPK8IP1 antibody (Mitogen-Activated Protein Kinase 8 Interacting Protein 1) (AA 470-498)

Details for Product anti-MAPK8IP1 Antibody No. ABIN652961, Supplier: Log in to see
Antigen
  • IB1
  • JIP-1
  • Jip1
  • Prkm8ip
  • Skip
  • mjip-2a
  • JIP1
  • Jip-1
  • Mapk8ip
  • PRKM8IP
  • mitogen-activated protein kinase 8 interacting protein 1
  • MAPK8IP1
  • LOC100344706
  • Mapk8ip1
Epitope
AA 470-498, C-Term
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7
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2
1
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1
Reactivity
Human
66
48
40
Host
Rabbit
71
2
1
Clonality (Clone)
Polyclonal ()
Conjugate
This MAPK8IP1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
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1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
58
31
16
13
8
7
3
3
2
2
1
Options
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Immunogen This JIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-498 AA from the C-terminal region of human JIP1.
Clone RB23000
Isotype Ig
Specificity This JIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477~506 amino acids from the C-terminal region of human JIP1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name JIP1 (MAPK8IP1 Antibody Abstract)
Background JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.
Synonyms: Mitogen-activated protein kinase 8-interacting protein 1, Islet-brain 1, IB-1, JNK MAP kinase scaffold protein 1, C-Jun-amino-terminal kinase-interacting protein 1, JNK-interacting protein 1, JIP-1, MAPK8IP1, IB1, JIP1, PRKM8IP
Molecular Weight 77524 DA
Gene ID 9479
UniProt Q9UQF2
Research Area Protein Modifications
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 470-498), (C-Term) antibody (ABIN652961) Western blot analysis of JIP1 Antibody (C-term) (ABIN652961) in MCF-7 cell line lysat...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 470-498), (C-Term) antibody (ABIN652961) Formalin-fixed and paraffin-embedded human brain tissue reacted with JIP1 Antibody (C...
Flow Cytometry (FACS) image for anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 470-498), (C-Term) antibody (ABIN652961) JIP1 Antibody (C-term) (ABIN652961) flow cytometry analysis of MCF-7 cells (bottom hi...
Background publications Mooser, Maillard, Bonny, Steinmann, Shaw, Yarnall, Burns, Schorderet, Nicod, Waeber: "Genomic organization, fine-mapping, and expression of the human islet-brain 1 (IB1)/c-Jun-amino-terminal kinase interacting protein-1 (JIP-1) gene." in: Genomics, Vol. 55, Issue 2, pp. 202-8, 1999 (PubMed).

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