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Acyl-CoA Thioesterase 8 (ACOT8) (AA 290-319), (C-Term) antibody

Details for Product No. ABIN653089, Supplier: Log in to see
Antigen
  • PTE1
  • zgc:101691
  • HNAACTE
  • PTE-1
  • PTE-2
  • PTE2
  • hACTE-III
  • hTE
  • Pte1
Epitope
AA 290-319, C-Term
17
17
3
3
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
53
22
19
2
Host
Rabbit
47
6
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
38
27
20
15
11
11
5
3
1
1
Supplier
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Immunogen This ACOT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-319 AA from the C-terminal region of human ACOT8.
Clone RB23177
Isotype Ig
Specificity This ACOT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290~319 amino acids from the C-terminal region of human ACOT8.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ACOT8 (ACOT8 Antibody Abstract)
Background Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. It may mediate Nef-induced down-regulation of CD4. It may be involved in the metabolic regulation of peroxisome proliferation.
Synonyms: PTE-2, Thioesterase II, hTE, hACTEIII, hACTE-III, HIV-Nef-associated acyl-CoA thioesterase, Peroxisomal long-chain acyl-CoA thioesterase 1, Peroxisomal acyl-coenzyme A thioester hydrolase 1, PTE-1, Acyl-CoA thioesterase 8, Choloyl-coenzyme A thioesterase, Acyl-coenzyme A thioesterase 8, PTE2, PTE1, ACTEIII, ACOT8
Molecular Weight 35914 DA
Gene ID 10005
UniProt O14734
Research Area Signaling, Protein Modifications, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Acyl-CoA Thioesterase 8 (ACOT8) (AA 290-319), (C-Term) antibody (ABIN653089) Western blot analysis of ACOT8 Antibody (C-term) (ABIN653089) in mouse liver tissue l...
Immunohistochemistry (IHC) image for anti-Acyl-CoA Thioesterase 8 (ACOT8) (AA 290-319), (C-Term) antibody (ABIN653089) Formalin-fixed and paraffin-embedded human Prostate carcinoma reacted with ACOT8 Anti...
Flow Cytometry (FACS) image for anti-Acyl-CoA Thioesterase 8 (ACOT8) (AA 290-319), (C-Term) antibody (ABIN653089) ACOT8 Antibody (C-term) (ABIN653089) flow cytometric analysis of MDA-MB435 cells (bot...
Background publications Choudhary, Kumar, Gnad et al.: "Lysine acetylation targets protein complexes and co-regulates major cellular functions." in: Science (New York, N.Y.), Vol. 325, Issue 5942, pp. 834-40, 2009 (PubMed).

Daub, Olsen, Bairlein et al.: "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." in: Molecular cell, Vol. 31, Issue 3, pp. 438-48, 2008 (PubMed).