Lysine (K)-Specific Demethylase 4B (KDM4B) (N-Term), (AA 4-31) antibody

Details for Product No. ABIN653341
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Antigen
Synonyms JMJD2B, TDRD14B, 4732474L06Rik, Jmjd2b, mKIAA0876, KDM4B, jmjd2b, si:ch211-124a3.4
Epitope
N-Term, AA 4-31
(13), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(60), (36), (31), (26), (25)
Host
Rabbit
(60), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(38), (20), (20), (10), (7), (6), (3), (2)
Pubmed 2 references available
Catalog no. ABIN653341
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This JMJD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-31 AA from the N-terminal region of human JMJD2B.
Clone RB23110
Isotype Ig
Specificity This JMJD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10~40 amino acids from the N-terminal region of human JMJD2B.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name JMJD2B
Background KDM4B / JMJD2B is a jumonji domain containing histone demethylase that specifically demethylates histone H3 at K9 and K36.
Synonyms: Jumonji domain-containing protein 2B, JmjC domain-containing histone demethylation protein 3B, Lysine-specific demethylase 4B, KIAA0876, JMJD2B, JHDM3B, KDM4B
Molecular Weight 121897 DA
Gene ID 23030
UniProt O94953
Research Area Protein Modifications
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Lysine (K)-Specific Demethylase 4B (KDM4B) (N-Term), (AA 4-31) antibody Western blot analysis of JMJD2B Antibody (N-term) (ABIN653341) in K562 cell line lysates (35 µg/lane). JMJD2B (arrow) was detected using the purified polyclonal antibody.
anti-Lysine (K)-Specific Demethylase 4B (KDM4B) (N-Term), (AA 4-31) antibody (2) Formalin-fixed and paraffin-embedded human Testis tissue reacted with JMJD2B Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Lysine (K)-Specific Demethylase 4B (KDM4B) (N-Term), (AA 4-31) antibody (3) JMJD2B Antibody (N-term) (ABIN653341) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Gray, Iglesias, Lizcano et al.: "Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein." in: The Journal of biological chemistry, Vol. 280, Issue 31, pp. 28507-18, 2005 (PubMed).

Beyer, Kristensen, Jensen et al.: "The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36542-52, 2008 (PubMed).

Hosts (60), (2)
Reactivities (60), (36), (31), (26), (25)
Applications (38), (20), (20), (10), (7), (6), (3), (2)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (13), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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