Hepcidin antibody (AA 17-46)

Catalog No. ABIN653413

This Rabbit Polyclonal antibody specifically detects Hepcidin in WB. It exhibits reactivity toward Human.

Quick Overview for Hepcidin antibody (AA 17-46) (ABIN653413)

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hepcidin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB22098

Product Details anti-Hepcidin Antibody

Binding Specificity: AA 17-46

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HAMP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the Central region of human HAMP.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:500. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Hepcidin

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Alternative Name: HAMP

Background: HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.

Molecular Weight: 9408

Gene ID: 57817

NCBI Accession: NP_066998

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis