KRT1 antibody (Cytokeratin 1) (AA 415-443)

Details for Product anti-KRT1 Antibody No. ABIN653648, Supplier: Log in to see
Antigen
  • CK1
  • EHK
  • EHK1
  • EPPK
  • K1
  • KRT1A
  • NEPPK
  • Krt-2.1
  • Krt2-1
  • Krt86
  • KRT1
  • Kb1
  • KER1
  • CK-1
  • Keratin-1
  • EpK
  • cytok
  • cytokeratin
  • epi-keratin
  • epiker
  • xK81
  • keratin 1
  • Keratin, type I cytoskeletal 47 kDa
  • KRT1
  • Krt1
  • xk81a1
Epitope
AA 415-443, Center
53
34
7
6
5
5
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
502
199
175
131
95
79
73
70
70
63
63
57
35
31
5
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Host
Rabbit
463
63
8
Clonality (Clone)
Polyclonal ()
Conjugate
This KRT1 antibody is un-conjugated
25
24
19
18
17
17
17
17
17
17
17
17
16
16
15
15
15
9
4
2
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
391
250
233
167
158
154
132
76
29
12
11
2
2
2
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen This KRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 AA from the Central region of human KRT1.
Clone RB18411
Isotype Ig
Specificity This KRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422~451 amino acids from the Central region of human KRT1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name KRT1 (KRT1 Antibody Abstract)
Background KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.
Synonyms: Hair alpha protein, Type-II keratin Kb1, 67 kDa cytokeratin, Keratin-1, K1, Cytokeratin-1, CK-1, Keratin, type II cytoskeletal 1, KRTA, KRT1
Molecular Weight 66039 DA
Gene ID 3848
UniProt P04264
Research Area Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Cytokeratin 1 (KRT1) (AA 415-443), (Center) antibody (ABIN653648) Western blot analysis of KRT1 Antibody (Center) (ABIN653648) in MCF-7 cell line lysat...
Immunohistochemistry (IHC) image for anti-Cytokeratin 1 (KRT1) (AA 415-443), (Center) antibody (ABIN653648) KRT1 Antibody (Center) (ABIN653648) IHC analysis in formalin fixed and paraffin embed...
Flow Cytometry (FACS) image for anti-Cytokeratin 1 (KRT1) (AA 415-443), (Center) antibody (ABIN653648) KRT1 Antibody (Center) (ABIN653648) flow cytometric analysis of MCF-7 cells (bottom h...
Background publications Labudova, Tomaskova, Skultety, Pastorek, Pastorekova: "The nucleoprotein of lymphocytic choriomeningitis virus facilitates spread of persistent infection through stabilization of the keratin network." in: Journal of virology, Vol. 83, Issue 16, pp. 7842-9, 2009 (PubMed).

Barcelos, Sotto: "Comparative analysis of the expression of cytokeratins (1, 10, 14, 16, 4), involucrin, filaggrin and e-cadherin in plane warts and epidermodysplasia verruciformis plane wart-type lesions." in: Journal of cutaneous pathology, Vol. 36, Issue 6, pp. 647-54, 2009 (PubMed).

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