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LCAT antibody (Lecithin-Cholesterol Acyltransferase) (AA 285-313)

Details for Product anti-LCAT Antibody No. ABIN653825, Supplier: Log in to see
Antigen
  • AI046659
  • D8Wsu61e
  • LCAT
  • lcat
  • MGC82035
  • MGC88964
Epitope
AA 285-313, Center
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13
11
10
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6
5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
88
40
38
3
2
1
1
Host
Rabbit
105
6
Clonality (Clone)
Polyclonal ()
Conjugate
This LCAT antibody is un-conjugated
13
10
5
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
77
52
20
16
13
13
11
11
6
2
1
Supplier
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Immunogen This LCAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-313 AA from the Central region of human LCAT.
Clone RB23365
Isotype Ig
Specificity This LCAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292~321 amino acids from the Central region of human LCAT.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LCAT (LCAT Antibody Abstract)
Background LCAT encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport.
Synonyms: Phospholipid-cholesterol acyltransferase, Lecithin-cholesterol acyltransferase, Phosphatidylcholine-sterol acyltransferase,LCAT
Pathways: Glycerophospholipid metabolism
Molecular Weight 49578 Da
Gene ID 3931
UniProt P04180
Research Area Signaling, Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.39 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-LCAT antibody (Lecithin-Cholesterol Acyltransferase) (AA 285-313) (ABIN653825) Western blot analysis of LCAT Antibody (Center) (ABIN653825) in K562 cell line lysate...
Immunohistochemistry (IHC) image for anti-LCAT antibody (Lecithin-Cholesterol Acyltransferase) (AA 285-313) (ABIN653825) LCAT Antibody (Center) (ABIN653825) IHC analysis in formalin fixed and paraffin embed...
Flow Cytometry (FACS) image for anti-LCAT antibody (Lecithin-Cholesterol Acyltransferase) (AA 285-313) (ABIN653825) LCAT Antibody (Center) (ABIN653825) flow cytometric analysis of K562 cells (bottom hi...
Background publications Weissglas-Volkov, Aguilar-Salinas, Sinsheimer, Riba, Huertas-Vazquez, Ordoñez-Sánchez, Rodriguez-Guillen, Cantor, Tusie-Luna, Pajukanta: "Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples." in: Circulation. Cardiovascular genetics, Vol. 3, Issue 1, pp. 31-8, 2010 (PubMed).

Voora, Shah, Reed, Zhai, Crosslin, Messer, Salisbury, Ginsburg: "Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response." in: Circulation. Cardiovascular genetics, Vol. 1, Issue 2, pp. 100-6, 2009 (PubMed).

McGeachie, Ramoni, Mychaleckyj, Furie, Dreyfuss, Liu, Herrington, Guo, Lima, Post, Rotter, Rich, Sale, Ramoni: "Integrative predictive model of coronary artery calcification in atherosclerosis." in: Circulation, Vol. 120, Issue 24, pp. 2448-54, 2009 (PubMed).