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Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (AA 81-107), (Center) antibody

Details for Product No. ABIN654106, Supplier: Log in to see
Antigen
  • fj66g02
  • zgc:73157
  • wu:fj66g02
  • Bcatc
  • BCATC
  • BCT1
  • ECA39
  • MECA39
  • PNAS121
  • PP18
  • BCATc
  • Eca39
Epitope
AA 81-107, Center
16
15
10
10
4
4
2
2
2
1
1
1
1
1
Reactivity
Human
75
31
24
6
4
4
4
4
2
2
Host
Rabbit
66
12
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
60
32
28
11
11
1
1
Supplier
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Immunogen This BCAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 AA from the Central region of human BCAT1.
Clone RB22413
Isotype Ig
Specificity This BCAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-115 amino acids from the Central region of human BCAT1.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BCAT1 (BCAT1 Antibody Abstract)
Background This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
Synonyms: Branched-chain-amino-acid aminotransferase, cytosolic,BCAT1,BCT1, ECA39
Molecular Weight 42966 DA
Gene ID 586
NCBI Accession NP_005495, NP_001171563, NP_001171562, NP_001171565, NP_001171564
UniProt P54687
Research Area Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (AA 81-107), (Center) antibody (ABIN654106) BCAT1 Antibody (Center) (ABIN654106) immunohistochemistry analysis in formalin fixed ...
Background publications Eijgelsheim, Newton-Cheh, Sotoodehnia et al.: "Genome-wide association analysis identifies multiple loci related to resting heart rate." in: Human molecular genetics, Vol. 19, Issue 19, pp. 3885-94, 2010 (PubMed).